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Oslo universitetssykehus HF
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Researcher

Engasjement stilling ∙ Heltid ∙ Oslo
  • Søknadsfrist 11.06.2025
  • Arbeidsspråk Engelsk
  • Sektor Offentlig

Kortversjonen

Conduct mechanistic studies on omegasome formation and closure using molecular/cell biology, fluorescence microscopy, and flow cytometry.

Kvalifikasjoner

  • PhD in cell biology, molecular biology, biochemistry, or equivalent
  • Experience in cloning, CRISPR/Cas9, cell culture, western blot, and flow cytometry
  • Hands-on experience with autophagy assays
  • Proficiency in fixed and live cell fluorescence microscopy and image analysis
  • Fluent in English (oral and written)

Hva vi tilbyr

  • Three-year employment (initially 2 years with a possible 1-year extension)
  • Salary according to Oslo University Hospital guidelines
  • Access to state-of-the-art imaging facilities
  • Weekly lab and institute seminars
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Researcher

A researcher position (postdoctoral level) is available in the Autophagy group of Prof. Anne Simonsen at the Institute for Cancer Research, Division of Cancer Medicine, Oslo University Hospital. The project will be supervised by Viola Nähse, Senior Scientist at Oslo University Hospital and Associate Professor at the Institute for Medical Biology, UiT The Arctic University of Norway.

The position is funded by the South-Eastern Norway Regional Health Authority (HSØ) and is available from August 15, 2025, for three years (initially two years, with the possibility of a one-year extension). Start date is negotiable.

The Autophagy group is based at the Radium Hospital, part of Oslo University Hospital, the largest academic hospital in Scandinavia. The group is affiliated with two Norwegian Research Centres:

  • Centre for Cancer Cell Reprogramming (CanCell) – a multidisciplinary center of excellence with six research groups focused on cancer cell identity and plasticity (https://www.med.uio.no/cancell/english/).
  • Autophagy Research Centre Targeting Cancer (ARCTiC) – established in 2024 to advance understanding of autophagy in cancer (https://arctic-autophagy.no/about-arctic/).

A major research goal is to uncover the molecular mechanisms of phagophore formation at omegasomes, a subdomain of the endoplasmic reticulum. We recently identified a mechanism for phagophore constriction at omegasomes, relevant for selective autophagy (https://www.nature.com/articles/s41467-023-39641-9).


Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!


Tasks and Responsibilities

The project will explore the mechanisms of omegasome formation and closure in response to DNA damage, including ionizing radiation. The work involves mechanistic studies using molecular and cell biology techniques, as well as fluorescence microscopy and flow cytometry to assess autophagy phenotypes.

Qualifications and Requirements

We are looking for a highly motivated, skilled, and independent researcher with the following qualifications:

  • PhD in cell biology, molecular biology, biochemistry, or equivalent
  • Strong experience in molecular and/or cell biology techniques, including cloning, CRISPR/Cas9, cell culture, western blot and flow cytometry
  • Hands-on experience with autophagy assays
  • Proficiency in fixed and live cell fluorescence microscopy and image analysis
  • Proven track record of scientific productivity (e.g., publications in international journals)
  • Experience with figure preparation and manuscript writing
  • A high level of research integrity, motivation, and willingness to learn new methods
  • Excellent teamwork and communication skills
  • Fluent in English (oral and written)

We Offer

  • A dynamic and innovative research project within a collaborative and supportive team
  • A stimulating environment with access to state-of-the-art imaging facilities
  • Weekly lab and institute seminars, and an excellent international research network
  • A healthy balance between independent research and close mentorship
  • Career development support and guidance
  • A full-time three-year employment (2 years + possibility for 1-year extension)
  • Salary according to Oslo University Hospital guidelines
  • A flexible, family-friendly workplace that supports work–life balance

How to Apply
Submit your application through Webcruiter with the following documents:
Application letter (1–2 pages) detailing your motivation and suitability for the position
Curriculum Vitae, including a list of publications and a summary of relevant skills
Contact information for two references from previous research environments

Incomplete applications (missing any of the above documents) or applications not submitted via Webcruiter will not be considered.
Application deadline: June 10, 2025
Preferred start date: August 15, 2025 (negotiable)

Ferdigheter
AI-generert

  • Celle- og molekylærbiologi
  • Cellekultivering
  • Flowcytometri
  • Fluorescense microscopy/imaging
  • Laboratorieteknikker
  • Molekylær kloning
  • Western blot

Om arbeidsgiveren

Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel. 
  • Sted: 0379 Oslo
  • Bransje: Forskning, utdanning og vitenskap
  • Stillingsfunksjon: Forskning/Stipendiat/Postdoktor

Nøkkelord

Forskning, Biologi, Kreftforskning

Spørsmål om stillingen

VN

Viola Nähse

Senior Scientist

Firmaets beliggenhet

0379 Oslo

Kart
Søknadsfrist: 11.6.2025

5038 følger dette firmaet

Nyttige lenker

Bli kjent med Oslo universitetssykehus

Annonseinformasjon

  • FINN-kode: 409052519
  • Sist endret: 5.6.2025, 13:31
  • Org.nr.: 993467049Se på Brønnøysundregistrene(åpnes i ny fane)
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